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Methylation pathways become saturated, and excess methionine is converted to homocysteine, which may contribute to cardiovascular risk if B-vitamin cofactors (B6, B12, folate) aren't adequate

Other skin cancers, such as squamous cell carcinoma, can also turn up as a dark spot on your lip

I'm not sure there is a way, short of a blood test, to tell.

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While finding protruding pedunculated stalk polyps and flat, plate-like sessile polyps is relatively straightforward, identifying subtle flat and serrated lesions presents a major challenge
