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We found that IKE + DHAA specifically induce lipid droplet peroxidation, a key event sufficient to trigger ferroptosis in IKE-resistant cancer cell

To date, three patterns of p-i-related hypersensitivity reactions have been proposed: the altered peptide model of p-i HLA, the allo-immune model of p-i HLA, and the p-i TCR model ( The altered peptide model of p-i HLA and the allo-immune model of p-i HLA were both developed because some ADRs generated by small molecule drugs are limited exclusively to the HLA allele (36)

*Correspondence: Ilke Pala-Ozkok [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Chowdhuri, S
Bull Exp Biol Med 2003;135:5979
