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Early and protective microglial activation in Alzheimers disease: a prospective study using 18F-DPA-714 PET imaging
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As comprehensively reviewed, lactate exhibits tissue specificity: in white adipose tissue, it can suppress lipolysis via the GPR81 receptor at high concentrations, yet promote lipolysis and browning via 3-adrenergic receptor and mitochondrial pathways at lower concentrations or under specific conditions such as exercise [149, 150]
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