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Simultaneously, the elevated levels of inflammatory factors exacerbate oxidative stress and DNA damage, which ultimately activates apoptotic signaling pathways, accelerating cell death

doi: 10.3389/fimmu.2018.01393 191 JahnkeSSchmidHSeckerK-AEinhausJDuerr-StoerzerSKeppelerHet al

(Lond.) 42 , 618624 (2018)

That selectivity profile is why ipamorelin became the default GHS-R compound for research protocols: you get the GH signal without the hormonal noise that comes with older GHRPs
