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IGF binding proteins modulate access of circulating IGF-I to the tissues and modulate IGF-I and -II access to the type 1 IGF receptor (IGF1R) at the cellular level

According to the National Institutes of Health, B-12 is also pivotal in regulating your metabolism the process through which your body converts food into energy, maintains healthy tissues, regulates your body temperature and allows for healthy organ function

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Athletes may be using these substances in the belief that they will give them an edge, although how common these illicit practices are is unknown, as they are shrouded in secrecy