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Description
This genotype is generally associated with typical TNF- production and balanced inflammatory signaling, allowing for effective immune responses without excessive or prolonged inflammation
[DOI] [PubMed] [Google Scholar] Nagy L
It is thought to affect 1 in every 3,000 people
Several studies reported that the clinical severity of the disease in the EAE model was significantly downregulated by curcumin, which was able to reduce the mRNA expression of IL-17, transforming growth factor (TGF)-, IFN-, IL-6, IL-21, IL-23, signal transducer and activator of transcription (STAT)3, and retinoic-acid-receptor-related orphan nuclear receptor gamma (RORt) (Kanakasabai et al., 2012), to modulate the CD4 + T cells and toll-like receptors (TLRs) (Chearwae and Bright, 2008
Glutathione is a natural body antioxidant, which helps preserve all other antioxidants
