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This study addressed key knowledge gaps by characterizing 48-h post-OCC plasma TMAO pharmacokinetics in high TMAO-producing adults and testing whether a single dose of a polyphenol-rich pomegranate extract alters the dynamic TMAO response rather than fasting levels alone

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Recently, increasing numbers of studies have reported the preventive effects of approved drugs for CIPN (Table 1)

After about two months, victims develop swollen and bleeding gums, loosened teeth, bleeding into the membranes covering the eyeballs, anemia, extreme dryness of the mouth and eyes, dry itchy skin, loss of hair, extreme weakness, aching legs, and severe joint pains

PP is a rare inflammatory skin disease (234)