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J Trace Elem Med Biol (2018) 50:498507
The approved uses of acamprosate are the maintenance of abstinence, prevention of relapse, and support in long-term recovery for individuals diagnosed with alcohol use disorder (AUD)

In addition, increased formation of extracellular superoxide and hydrogen peroxide occurs during immune responses
A clinical study investigating oxidative DNA damage in AD reported increased oxidative DNA damage in patients with AD and its correlation with alcohol withdrawal severity

Damage can develop in various tissues if antioxidant defences are lacking [143]
