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Moreover, in head and neck squamous cell carcinoma, CAFs increase the stromal stiffness of the tumor niche by remodeling the biomechanical properties of the TME

Siegel GJ, Agranoff BW (1999) Basic neurochemistry: molecular, cellular, and medical aspects
Additionally, it has no notable effects on BMI, systolic, or diastolic BP

Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis

Estrogen and increased spine density are also associated with improvements in learning and memory in rodent models 7072
