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As an ATP rate-limiting enzyme, CoQ10 regulates redox reactions, protecting mtDNA and mitochondrial membranes from radical attack and modulating energy production rates (Wang et al., 2024)

NAC as a Pharmacological Chaperone NAC is hypothesized to bind and stabilize misfolded proteins and route them correctly within the cell, thereby facilitating their activity by acting as a pharmacological chaperone

Additionally, IL-5 inhibitors have minimal impact on lung function metrics such as FEV 1 , and some studies have even observed no improvement or a decline in lung function, suggesting they may struggle to reverse the core pathological change of airflow limitation