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Impaired FAD-dependent enzyme activity is also detrimental to bloodbrain barrier (BBB) integrity, leading to downregulation of tight-junction proteins such as claudin-5 and occluding, increased permeability, and enhanced peripheral immune infiltration
ANGPT-2 weakens the interactions between endothelial cells and smooth muscle cells, responsible for endothelial cell migration (Maisonpierre et al., 1997)
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[DOI] [PubMed] [Google Scholar] 74.Burk R.F
The double-edged functions of necroptosis
