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For example, the long-term supplementation of foods that are rich in omega-3 ( n-3 ) polyunsaturated fatty acids (PUFA) [285], vitamins such as vitamin A [286], B or folate [287], C, E [288], and D [289], carotenoids such as lutein and zeaxanthin [290,291], polyphenols [292], fiber [293], greater adherence to the Mediterranean diet, or a diet rich in vegetables and fruits (whole grains, nuts, tea, coffee, and legumes) or consumption of eggs, fish, seaweed, minerals such as copper, iron, magnesium, and calcium [294,295,296,297], delay the shortening of the TL in older adults through glycated hemoglobin (HbA1c) [284,288]

NRF2 in Amyotrophic Lateral Sclerosis ALS is the most common motor neuron disease in adults and estimates have reported that 31,000 patients live with ALS in the US, where on average 5,000 new patients are diagnosed annually (Mehta et al., 2023)

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YuanHZhangJNageswaranDLiL.Carotenoid metabolism and regulation in horticultural crops