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Today: Proc., 2022, 71, 254258 CAS

The synthetic micro-neurotrophin BNN27, which binds specifically to TrkA and p75NTR, protects mature oligodendrocytes against cell death in a cuprizone-induced model of demyelination in a TrkA-dependent manner in vitro and protects against myelin loss and reduces microgliosis and astrocytosis in an in vivo mouse model