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Despite the preclinical promise shown by pharmacological agents that target ferroptosis-such as inducers like erastin and RSL3, and inhibitors like fer-1-their application in clinical settings encounters difficulties, which include unintended effects and restricted tissue specificity [2, 99]

Measurement of NVC in humans To evaluate NVC responses, a transcranial Doppler ultrasound system (DWL Multi-Dop T digital, Singen, Germany) with 2-MHz transducers was used

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