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409 So far, the RISM approaches have been less widely used than implicit-solvent modeling because of the greater computational expense of RISM

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Mood can also influence drinking tendency and speed, thus altering BAC

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While additional studies are needed to determine whether elevated vitamin B 12 status may be related to cancer development, including evaluating whether it might be a potential marker of cancer, it is important for observational studies to adequately control for potential confounders, such as age, menopausal status, alcohol use, and intake of the B-vitamin folate