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Moreover, studies highlighted that the AKT signaling pathway is important to fibroid development under hypoxic environments and seems to be activated by oxidative stress [13]
Communications 9 (1), 2873

HD has been hypothesized to be caused by an abnormal expansion of the polyglutamine repeat at the N-terminus of the mutant Huntingtin (HTT) protein, leading to brain atrophy primarily within the striatum and cerebral cortex

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Nonetheless, the safety profile remains favorable, with no significant adverse effects linked to SFN in multiple trials, supporting its potential as a long-term therapeutic option
