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The nonthermal effects of ultrasound are mediated by ultrasonic pressure, acoustic flow, shock waves, liquid microjets, and oscillation or cavitation, which can be adapted to control the release of BAPPs

The 12mg weekly arm produced a 24.2% mean body weight reduction over 48 weeks, with 26% of participants achieving at least 30% total body weight loss a threshold previously unattained by any pharmacological intervention in a clinical trial setting
