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doi: 10.1016/j.humimm.2021.09.004 62 RoeKGibotSVermaS

Therefore, it is recommended that synergy studies should calculate the fractional inhibitory concentration index (FICI), defined as: Table 1

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The n-shaped doseresponse curve could account for the mixed results of previous studies that tested the effect of a single dose level of Vitamin-B6, which in some cases was either a mega dose 10 or 20 times greater than used here, or a smaller dose than the 100 mg used here, to produce beneficial effects in autism (Li et al., 2018