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Activation of NF-B signaling pathway aggravates the inflammation of UC The NF-B signaling pathway is a central regulator of inflammation

The compound's unique -peptide bond between glutamate and cysteine renders it resistant to degradation by common peptidases, allowing intracellular accumulation to protective concentrations

[DOI] [PubMed] [Google Scholar] Giardina T., Biagini A., Dalle Ore F., Ferre E., Reynier M., Puigserver A

Moreover, lysophosphatidylcholine accumulation in the lung may increase the permeability of alveolar epithelium, disrupt lung surfactant, and stimulate pro-inflammatory lung microenvironment 42

Balmforth M