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B12 is water-soluble, and its generally safe even at very high doses

The FDA warns persons with the following conditions should not use this drug: coronary heart disease, uncontrolled high blood pressure, hyperthyroidism, who have a history of drug abuse, pregnant women and nursing mothers

Observational Study of B12 in Fortified Non-Dairy Milks Because Yamada et al

These are similar to vitamin B12, but theyre not bioavailable and so will not improve your intake of the vitamin

Studies utilizing models of myocardial infarction have demonstrated reduced infarct size, improved cardiac function, and enhanced neovascularization following TB-500 treatment