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The antibodies used are shown as following: Rat CD3 FITC G4.18, CD4 APC OX-35, and CD8a PE OX-8 (BD Pharmingen, Franklin Lake, NJ,USA)

214217 Additionally, sensory neurons in the dorsal root ganglia (DRG) exhibit altered phenotypes, such as reduced neurofilament synthesis, endoplasmic reticulum stress, and changes in key plasticity molecules, such as growth-associated protein 43 (GAP43) and heat shock proteins, leading to mitochondrial dysfunction and loss of peripheral nerve function

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