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Description
Cancer cells utilize glutamine metabolism-related branched pathways involved in the development of drug resistance Glutamine synthetase (GS), an enzyme that functions at the origin of glutamine metabolism, is the sole regulatory factor that governs glutamine synthesis from its fundamental stages, thereby playing a pivotal role in the progression of cancer [213]

Vetrano DL Article: GEROSCIENCE

Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations

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Without sufficient GSH and NADPH, the cell cannot neutralize ROS that are produced naturally elsewhere in the cell
