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389 L-Tryptophan and 5-Hydroxytryptophan L-tryptophan, the amino acid precursor to serotonin in the intestines and brain, is an important mediator of communication between the gut and the central nervous system

though statistically different, P 95% in the knee joints (Table 3)

Eur J Biochem 231:236241

In the latter organ, CRH alone or in combination with AVP stimulates corticotropic cells to release proopiomelanocortin (POMC), which is an ACTH precursor

It also increases vascular flow to the tendons and ligaments to increase healing and can also help aid skin burns to heal faster and increase blood flow to damaged tissues