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Approximately 20% of KRAS-mutant LUAC patients carry loss-of-function KEAP1 (Kelch-like epichlorohydrin-related protein-1), a negative regulator of NRF2

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These issues were investigated in this work using the yeast Saccharomyces cerevisiae

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10.1016/j.biotechadv.2011.08.007 54 GeorgievV.SlavovA.VasilevaI.PavlovA

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Findings from preclinical research suggest that the peptide plays a role in maintaining intestinal barrier stability and supporting cytoprotective mechanisms within the gastrointestinal tract

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female ob / ob ), n = 6 mice (male ob/ob , EB1002), n = 11 mice ( Mc4r KO, vehicle), n = 8 mice ( Mc4r KO, EB1002))

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