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3 NASH is associated with increased risks of fibrosis, cirrhosis, liver failure, and liver cancer
Kang et al., 2013
Additionally, although it does not cause systemic coagulopathy in mice, TMAO does downregulate thrombomodulin in human endothelial cells
Further, heat shock induction of slo mimicked the lowering effect of alcohol on seizure threshold, suggesting a role for slo induction in the susceptibility to withdrawal seizures
SMCs: smooth muscle cells
