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First, hydrolysis: in aqueous solution, peptide bonds can be cleaved by water at a rate accelerated by heat, extreme pH, and metal ion contamination

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Potential Side Effects and Precautions While methylcobalamin injection is generally considered safe, some people might experience minor side effects, such as: Pain or redness at the injection site Mild diarrhea Headache or nausea Rare allergic reactions In patients with kidney issues or those on certain medications, methylcobalamin must be used cautiously