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doi: 10.1523/ENEURO.0103-18.2018 85 PillotBDuraffourdCBgeotMJolyALuquetSHouberdonIet al

Glutathione has also been shown to increase glutamate agonistevoked DA release in mouse striatal neurons.23 Use in psychiatry There is a growing body of literature exploring the use of NAC in the treatment of psychiatric illness

Notably, HIF-1 mediates adaptive metabolic responses to hypoxia by enhancing glycolytic pathway, serine synthesis and one-carbon metabolism to promote mitochondrial antioxidant production (NADPH and GSH), and inhibiting the TCA cycle so as to diminish mitochondrial ROS production (247)

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Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: can early neural stem cell grafting intervention provide protection