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When ferroptosis is induced by exogenous or internal stimuli, polyunsaturated fatty acids (PUFAs) are oxidized by intracellular ROS that arise from iron-dependent Fenton reactions

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For example, a 2023 RCT revealed that only a subset of adults experienced substantial alterations in gut microbiota and metabolic markers following a standardized probiotic, with responses closely associated with baseline community composition (573)

Xu D, Yan S, Yin J, Zhang P (2011) Null genotype of GSTT1 contributes to colorectal cancer risk in Asian populations: evidence from a meta-analysis
