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In evaluating risks and benefits, the IRB should consider only those risks and benefits that may result from the research (as distinguished from risks and benefits of therapies that subjects would receive even if not participating in the research)

This can be done through a balanced diet that includes foods rich in glutathione or its precursors

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The transdermal route could be considered for patients who prefer not to use oral or injectable medications

[147] Healthcare providers should consider starting with lower initial doses in elderly patients and titrating based on clinical response and tolerance