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Hormonal interactions are not a documented concern at research doses

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Possibly, reduced activity of eNOS and COX2 may be an effect of BPC 157, in particular substituting the NO effect, whether an additive and/or synergistic effect, related to the activity of BPC 157 administration in isoprenaline-treated rats with infarction and reinfarction

doi:10.1093/advances/nmy057

30 A 2021 meta-analysis on the effects of B12 on cognitive function found no benefit with either B12 alone (based on four RCTs) or B12 combined with other B vitamins (based on 13 studies)