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Regarding diabetic nephropathy, results of studies on diabetic rats showed that ALA exerts a strong protective effect on diabetic kidneys [65] and that oral ALA supplementation is able to prevent early development and progression of diabetic nephropathy acting as an anti-hyperglycemic, antioxidant, anti-inflammatory, anti-fibrotic and anti-apoptotic compound [66]

Applied topically, it uses the same mechanism to promote lipid breakdown in subcutaneous tissues, making it a valued active in treatments targeting cellulite

Various gluten analogues (structurally similar to gluten) have been developed that effectively bind and inhibit HLA DQ2, which is present in over 90% of cases of celiac disease (Juse 2010

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