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Increases Mobility For People With Peripheral Artery Disease When the peripheral arteries become clogged by plaque, peripheral artery disease occurs which commonly take place in the legs

BMJ (Clinical research ed.) 380:24 Tang S, Zhang C, Oo WM, Fu K, Risberg MA, Bierma-Zeinstra SM, Neogi T, Atukorala I, Malfait AM, Ding C, Hunter DJ, Osteoarthritis (2025) Nat Reviews Disease Primers 11(1):10 Li H, Yuan Y, Zhang L, Xu C, Xu H, Chen Z (2024) Reprogramming macrophage polarization, depleting ROS by astaxanthin and thioketal-containing polymers delivering rapamycin for osteoarthritis treatment

This problem gets worse because the mitochondria, the engines that burn glucose to provide energy, were also not working well in the brain

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Gastroenterology 155 , 629647 (2018)