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These indirect assays precisely measure SOD activity by assessing the attenuation in the rate of a chromogenic reaction critically dependent on superoxide presence

For aerobic respiration the oxidation of NADH occurs during tricarboxylic acid cycle (TCA) and for fermentation it occurs at the time of conversion of pyruvate to lactate by lactate dehydogenase enzyme (Figure 3b)

Tullius, USA Mentor A SHIFTING BALANCE: INNATE IMMUNITY IMPACTS CHARACTERISTICS AND SPECIFICITY OF ALLOIMMUNE RESPONSES IN AGING

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