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Signs and symptoms [edit] The symptoms vary depending on the SMA type, the stage of the disease, as well as individual factors

2018 Dec 24;16(1):371

Mechanistically, TMAO inhibits megalin expression via PI3K/ERK, reducing albumin uptake and promoting tubular cell dysfunction, which triggers tubulointerstitial inflammation and fibrosis (Kapetanaki et al., 2022)

Thevenet, J

Exercise regulation of marrow adipose tissue
