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Description
CYP1A1 has been shown to regulate intracellular iron levels and contribute to the production of ROS through the Fenton reaction
Moreover, the buildup of free heme and labile iron triggers the pathological oxidation of proteins, lipids, and DNA by ROS
Cuenod, M
The angiotensin II type 1 receptor-neprilysin inhibitor LCZ696 blocked aldosterone synthesis in a human adrenocortical cell line
Statistical analysis was carried out with Graphpad Prism 6 as described in the figure legends
