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Moreover, dietary interventions such as fasting and resveratrol supplementation have been found to enhance SIRT1 activity, influencing transcription factors such as Forkhead box O3 (FOXO3) and Forkhead box O1 (FOXO1), which improve superoxide dismutase (SOD) activity and reverse oxidative stress-induced acetylation, contributing to liver protection (Hardiany et al., 2023

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