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For instance, anthocyanin-derived metabolites such as protocatechuic acid (100 mg/kg after onset until death, 1 time/day, 5 times/week) (67) and anthocyanin-enriched strawberry extract (2 mg/kg/day after 60 days of age until death) (68), were shown to attenuate spinal cord astrogliosis, inhibit motor neuron apoptosis, and preserve neuromuscular junction integrity in SOD1 mutant micea widely used ALS model

doi: 10.3390/antiox10060890 20 GanttKRGoldmanTLMcCormickMLMillerMAJeronimoSMBNascimentoETet al

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However, this absorption method occurs only to a limited extent

It results from interactions, in the presence of UV, between oxygen O 2 , nitrogen oxides (NO and NO 2 ) and volatile organic compounds (VOC)