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In yeast, 12-hydroxyeicosatetraenoic acid (which is probably a product of GPX4 depletion in mammals) is a substrate for Atg8 (MAP1LC3 [microtubule-associated protein 1 light chain 3] in mammalian cells) lipidation required to activate autophagy [156]
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Also, in some studies, PNPs have been used to increase the effectiveness of proven treatments
M., Chou M
