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Description
In vivo assays confirmed that BRWD3 binds cry in a light-dependent manner and, as a part of the BRWD3-Cullin4-RING Finger E3 Ligase (CRL4) complex, catalyzes cry ubiquitination and subsequent proteasomal degradation (Ozturk et al., 2013)
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It is also a key building block for hemoglobin, which is essential for healthy red blood cells and oxygen transportation
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