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Downturned mouth corners The depressor anguli oris (DAO) pulls the mouth corners down, contributing to a sad or stern resting expression

10.1016/S0140-6736(19)30417-9 71 HunterD

Future research should prioritize the identification of actionable targets within the ferroptotic pathway, assess the regulatory potential of natural compounds and traditional medicines on iron metabolism, and accelerate translational efforts to incorporate ferroptosis-modulating strategies into clinical practice (Table 1)

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