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Rescuing the function of mutant p53

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[DOI] [PMC free article] [PubMed] [Google Scholar] 405.Brown R.A

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Tumor-derived exosomes could restrain DC maturation, down-regulate the expression of surface markers like CD80, CD86, and MHC-II, and up-regulate the expression of CD11b and PD-L1, which ultimately obstructed the anti-tumor activity of Teff and reinforced immune evasion [185,186,187]

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