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One study did demonstrate that the multivitamin used for treatment resulted in improvements in biomarkers of energy metabolism (as well as oxidative stress) suggesting that the effect of the multivitamin may have been at least partially related to improvements in mitochondrial function ( in vitro assessment of compounds that may improve mitochondrial function in individuals with ASD ( Folate metabolism Several lines of evidence point to abnormalities in folate metabolism in ASD

Toxicol Pathol 25, 5360

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