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Cell viability was assessed using the MTT assay

Our analysis demonstrates that thiamine insufficiency restricted to the gastrointestinal system, i.e., lacking well-known symptoms of dry and wet beriberi, may arise through (i) a disbalance between the nutrient influx and efflux in the gastrointestinal system due to increased demands of thiamine by the organism

All such bicyclic pathways are collectively referred to as one-carbon metabolism

Glutathione for Neuropathy: A Powerful Antioxidant for Nerve Health By Bob Berendsen March 25, 2025 Neuropathy, often caused by diabetes, chronic inflammation, or toxicity, results in nerve damage that leads to pain, numbness, and weakness