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Another potential therapeutic target is the kinase CDK8, which, as a Mediator subunit, is often amplified in and is required for -catenin-dependent transcription and proliferation of colon cancer cells (Firestein et al., 2008

[DOI] [PubMed] [Google Scholar] 17.Tetlow N., Board P.G

Therefore, it has been proposed to increase the endogenous antioxidant enzyme pathway to prevent aminoglycoside-induced ototoxicity

This library consisted of two hundred human tryptic phosphopeptides frequently observed in large-scale phosphoproteomics experiments
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