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Soybean isoflavones ameliorate ischemic cardiomyopathy by activating Nrf2-mediated antioxidant responses

Specific roles of different PRDX isoforms in tumor-promoting, tumor-suppression as well as tumor treatment resistance have been reviewed previously for different cancers [106] with a number of specific applications to different cancer types including for example breast [107], lung [108] or pancreatic cancers [109]

Results: MFH compounds converge on Nrf2/ARE activation, NF-B suppression, autophagy promotion, and mitochondrial stabilization

however, they are context dependent and not required for the glucose-lowering effect of ketones [123, 125, 127]

Notably, high concentrations of cysteamine can inhibit -glutamylcysteine synthetase (-GCS), leading to depleted intracellular GSH stores and exacerbating oxidative stress-related conditions 12,13