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Elastin and its degradation products have multiple roles in the oncologic process

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Patients randomized to metformin therapy in the Diabetes Prevention Program Outcome Study were more likely to show vitamin B12 deficiency or borderline low vitamin B12 levels (19)

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To validate NNMT as an anti-obesity drug target, we investigated the permeability, selectivity, mechanistic, and physiological properties of a series of small molecule NNMT inhibitors