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Excessive accumulation of ROS leads to oxidative damage to biomolecules (such as DNA, proteins, and lipids), thereby inducing oxidative stress in cells

They were randomly divided into three groups (three mice per group) and injected intravenously through the tail vein with free DOX/SOR, D/S@MM, and D/S@SPMM, with 5 mg DOX/kg and 1 mg SOR/kg

BDNF mRNA 32% stressed Semax +18% above naive

N-Acetylcysteine Attenuates the Anxiety-Like Behavior and Spatial Cognition Impairment Induced by Doxorubicin and Cyclophosphamide Combination Treatment in Rats
