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Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), have become the leading causes of chronic liver disease worldwide, with increasing rates of cirrhosis, hepatocellular carcinoma, and cardiovascular complications

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Inoltre, lutilizzo di acido valproico pu comportare laumento dei livelli di ammoniaca nel plasma e linsorgenza di encefalopatia

Further, it acts as an E3 ubiquitin ligase and degrades several cellular proteins [54-57]