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Others may need to discontinue if symptoms are intolerable

IC + RL rats (ligations removed, exaggerated reperfusion)) or later, with an already-advanced injury course (IC+OB rats)

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HPG Axis Signalling and Spermatogenesis Research Luteinizing hormone-driven testosterone is central to spermatogenesis, with LH acting on Leydig cells to stimulate steroid production and intratesticular testosterone binding to androgen receptors on Sertoli cells influencing gene transcription and paracrine signalling required for germ cell development

If they think they may have a B12 deficiency, a blood test can determine this