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After ONI, they are converted to a reactive state by microglia-derived cytokines interleukin 1 (Il-1), tumor necrosis factor (TNF) and C1q, and acquire a neurotoxic phenotype that contributes to RGC loss [190]

Taken together, these factors suggest that the current body of evidence does not yet support PBM as an evidence-based treatment for dry AMD

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The peripheral neuropathy of vitamin B12 deficiency
